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AUTONOMIC DISORDERS

Diseases or syndromes
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  Amyloidosis
  Catecholamines
  Congenital
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  Infections
  Localized dysfunction
  Paraneoplastic
  Primary dysautonomia
  System degenerations
  Systemic diseases

System disorders
  Cardiac
  Gastrointestinal
  Hypotension
  Lacrimation
  Ocular & Pupils
  Pandysautonomia
  Respiratory
  Sexual
  Sweating
  Urinary

Other
  Physiology & Pharmacology 
  Pavlov laboratory
  External links
    Canine dysautonomia
    Pupil disorders

From Horsley Gantt


AUTONOMIC DISEASE SYNDROMES


AUTONOMIC SYNDROMES: System disorders

Acute
Cardiac
Gastrointestinal
Hypotension
Lacrimation
Ocular
Pandysautonomia
Respiratory
Sexual
Sweating
Urinary


Pandysautonomia: Autoimmune; Acute, Sub-Acute or Chronic 16
Dysautonomia + CNS syndrome 33
Gastrointestinal syndromes

Achalasia
Acquired
Chagas
Congenital absence of pain
Hirschsprung's
  Goldberg-Shprintzen
  Mowat-Wilson
Multiple endocrine neoplasia 2B
Paraneoplastic
Post-surgical
Visceral
  Myopathy
    + Ophthalmoplegia
    Dominant: ACTG2
    Multisystem: ACTA2
  Neuropathy



Heart rate: Parasympathetic control

Postural hypotension (Blood pressure: Sympathetic, noradrenergic control)

Other blood pressure disorders

Sweating: Sympathetic; Muscarinic cholinergic control

Hyperhidrosis
Anhidrosis




Urinary

Sexual dysfunction

Ocular

Adie
Horner's
Ross
Muscarinic AChR disorders
Actin smooth muscle disorders
Other pupil disorders
  Congenital MG
    Acetylcholinesterase (AChE) deficiency
  Hereditary neuropathy
    2J (P0 mutations)
    HSAN 2B
  Miosis
    Tubular aggregate myopathy (Stormorken)
      TAM1: STIM1
      TAM2: ORAI1

From: Monique Ryan
Congenital Horner's: Iris heterochromia


Absence of lacrimation (Alacrima)
Respiratory disorders, Autonomic

Multiple Systems Atrophy (Shy-Drager)

  Sporadic or Autosomal Dominant

Riley-Day (HSAN 3) 19

  Inhibitor of κ light polypeptide gene enhancer in B cells, kinase complex-associated protein (IKBKAP) ; Chromosome 9q31.3; Recessive

Congenital sensory neuropathy with anhidrosis (HSAN 4)

  TRKA/ NGF receptor (NTRK1) ; Chromosome 1q23.1; Recessive

Lethal autonomic sensory neuropathy (HSAN 6) 28

  Dystonin (DST) ; Chromosome 6p12.1; Recessive

Parkinson disease, juvenile onset

  Parkin ; Chromosome 6q26; Recessive

Dopamine β-Hydroxylase deficiency

  Chromosome 9q34.2; Recessive

Dopamine receptor D4

  Chromosome 11p15.5; Recessive


Hereditary Orthostatic Hypotension

  Chromosome 18q; Dominant

Aniridia, Type 2

  Paired box gene 6 (PAX6) ; Chromosome 11p13; Dominant

Achalasia-Addisonianism-Alacrimia (AAA) syndrome (Allgrove) 11

  AAAS (Aladin) ; Chromosome 12q13.13; Recessive

Achalasia-Alacrimia-Intellectual Dysfunction 32

  Guanosine diphosphate (GDP)-mannose pyrophosphorylase A (GMPPA) ; Chromosome 2q35; Recessive

Autoimmune polyendocrinopathy-Candidiasis-Ectodermal dystrophy (APECED)

  Autoimmune regulator (AIRE) ; Chromosome 21q22.3; Recessive

Postural Orthostatic Tachycardia Syndrome (POTS) 2


Hypotension in the elderly 6


Adult-onset Leukodystrophy (ADLD) 3

  Lamin B1 ; Chromosome 5q23.2; Dominant

Cold-Induced Sweating Syndrome 12

  Cytokine receptor–like factor 1 (CRLF1) ; Chromosome 19p13.11; Recessive

Cold-Induced Sweating Syndrome 2

  Cardiotrophin-like cytokine factor 1 (CLCF1) ; Chromosome 11q13.2; Recessive

From: M Al-Lozi

Harlequin Syndrome





Neuronal Intranuclear (Hyaline) Inclusion Disease (NIID)

  Dominant or Sporadic

Dementia with Lewy bodies 20


Pavlov lab
From Horsley Gantt

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12/10/2014