Neuromuscular

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NEUROMUSCULAR DISORDERS & ENDOCRINE DISEASE

Acromegaly
Adrenal
Carcinoid myopathy
Corticosteroid
Diabetes
Gonadal
  Dysgenesis
  Gynecomastia
  Hypogonadism
Insulinoma
Parathyroid
  Hyperparathyroid
  Hypoparathyroid
Thyroid
  Hyperthyroid
  Hypothyroid

From Bramwell: Atlas of Clinical Medicine

Myxedema




THYROID DISEASE

Hyperthyroid
  Myopathy
  Ophthalmopathy
  Other associated disorders
Hypothyroid
  Adult
  Childhood
  Other associated disorders

External link: Testing

From Bramwell: Atlas of Clinical Medicine


Hypothyroidism


Dercum 1894

Hyperthyroidism


From T Miller

Hyperthyroid


Hyperthyroid after treatment

Booth 1894


PARATHYROID DISEASE

Hypoparathyroidism



Hyperparathyroidism



ADRENAL & CORTICOSTEROIDS

Corticosteroid Potencies
Drug Potency
Gluco- Mineralo-
SHORT-ACTING
Hydrocortisone 1 1
Cortisone 0.8 0.8
INTERMEDIATE-ACTING
Prednisone 4 0.25
Prednisolone 4 0.25
Methylprednisolone 5 <0.01
Deflazacort 5.2 ?
Triamcinolone 5 <0.01
LONG-ACTING
Paramethasone 10 <0.01
Betamethasone 25 <0.01
Dexamethasone 30–40 <0.01
Adrenal insufficiency
Corticosteroid-binding globulin deficiency
Corticosteroid myopathy
Corticosteroid withdrawal
Myosin loss myopathy
Nelson

From Pincus Taft

Cushing's Syndrome



From Pincus Taft

Corticosteroid myopathy
Myosin loss myopathy


Nelson's syndrome: After total bilateral adrenalectomy
Adrenal insufficiency

From Bramwell: Atlas of Clinical Medicine

Addison's Disease

Fatigue syndrome with corticosteroid-binding globulin deficiency

  SERPINA6 ; Chromosome 14q32.1; Dominant
Corticosteroid withdrawal

ACROMEGALY
Cushing: The pituitary body & its disorders

Before disease

Disease onset

12 yrs of disease

17 yrs of disease

Square hand


Phalanges:
Tufting; Exostoses


Putnam

ACROMEGALY




CALCIPHYLAXIS 6




Hypoglycemic Neuropathy 5



Gynecomastia & Neuromuscular


Gonadal Disorders



Return to Neuromuscular Home Page

References
1. JNNP 2000;68:681-2
2. Ann Int Med 2000;133:197-201
3. Semin Neurol 2000;20:43-54
4. Muscle Nerve 2000;23:1891-1894
5. Acta Neuropathol 2001 (On-line)
6. Lancet 2001;358:1115-1116; Kidney Int 2001; 60:324-332
7. Eur J Neurol 2003;10:87-90
8. Ann Intern Med 2005;142:310
9. Arq Neuropsiquiatr 2004;62:154-157
10. Endocr Res 2005;31:171-175
11. American Journal of Medicine 2005;118:1340-1346

2/25/2014