Neuromuscular

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VITAMIN, MINERAL & NUTRITION RELATED SYNDROMES

Minerals
  Copper deficiency
  Iron
  Selenium deficiency
Vitamins
  A: Retinoids
  B1: Thiamine
  B2: Riboflavin
  B12 deficiency
  Biotin
  D
  E
    Deficiency
    Intoxication
  Niacin
  Folate
  Pyridoxine
    Deficiency
    Intoxication
MULTIFACTORIAL
Alcoholism
Celiac disease
Critical illness polyneuropathy
Cuban neuropathy
Postgastroplasty (Bariatric surgery)
Strachan's

Also see
  GI disorders
  Toxic disorders
    Muscle
    Nerve


Vitamin & Toxic Disorders: Symptom features


Thiamine (B1) deficiency (beri-beri)
Thiamine
B1 Biochemistry
Deficiency
  Clinical
  Laboratory
Thiamine disorders


Riboflavin

Riboflavin (B2) related syndromes



Niacin (Nicotinic acid) deficiency


Pyridoxine intoxication
Pyridoxine


Pyridoxine deficiency 15


Vitamin B12 (Cobalamin) deficiency

Putnam
Causes
Clinical features
Testing

Vitamin B12


Vitamin E deficiency
Vitamin E (α-tocopherol)


Hypervitaminosis E

Vitamin D deficiency 5
1,25-Dihydroxy Vitamin D3


Biotin deficiency
Biotin


Retinoid (Vitamin A derivatives) toxicity

Cuban epidemic neuropathy 1

Bariatric surgery (Postgastroplasty) syndromes: Polyneuropathy +

Selenium Deficiency 3, 4

Copper Deficiency & Disorders





MRI: Copper Deficiency
Posterior column T2 signal

Copper deficiency: Acquired
Copper smelting: Associated with Arsenic toxicity


Copper-associated disorders: Inherited
Copper: Animal disorders
Iron Disorders

Folate deficiency: Neuropathy 14


Critical Illness Neuropathy
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1. Curr Opin Neurol 1998;11:539-544
2. Textbook of Clinical Neurology 1998 pp 798-809
3. JNNP 1999;67:829-830
4. Muscle Nerve 1998;21:637-639, 2003;Online January
5. Arch Int Med 2000;160:1199-1203, Can J Neurol Sci 2009;36:336-339
6. Immunology Today 2000;21:348-354
7. Neurology Today 2003;61:273-274, Arch Neurol 2003;60:1303-1306; Arch Neurol 2003;60:1782-1785
8. Ann Neurol 2004; Online March
9. Neurology 2004;63:1462–1470
10. Ann Neurol 2003;54:19-29
11. Muscle Nerve 2006;34:789-793
12. Neurobiol Dis 2006;23:725-730
13. NEJM 2013;368:149-160
14. Neurology 2015;84: Online Feb
15. J Clin Neuromuscul Dis 2014;16:25-31

Some illustrations from MW King

7/21/2015