NEUROPATHY
Differential Diagnosis  
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FUNCTIONAL
INVOLVEMENT		 ANATOMICAL
DISTRIBUTION		 TIME COURSE NERVES Vesalius
Vesalius
  Motor
  Sensory
    · Hereditary
    · Pain
    · Small Fiber
    · Large Fiber
    · Large and Small Fiber
    · Neuronopathy
  Autonomic
Many polyneuropathies have
both motor and sensory
involvement.

   Asymmetric
  Bulbar
  Cranial Nerve Involvement
  Proximal
    · Motor
    · Sensory
  Upper Extremity


Many polyneuropathies are:
  · Symmetric
  · Most prominent
        Distally & in Legs.
   Acute
    Immune
  Infantile Weakness
  Childhood Onset
  Hereditary
    · Motor-Sensory
    · Motor Syndromes
    · Sensory Syndromes
  Relapsing
   Cranial
  Upper extremity
    Cervical root
  Lower extremity
    Lumbosacral root

  Axillary
  Median
  Musculocutaneous
  Peroneal, Common
  Radial
  Suprascapular
  Ulnar
GENERAL ASSOCIATED FEATURES LABORATORY
Chronic immune neuropathies
  · Demyelinating
  · Axonal

Immunomodulating therapies

Muscle innervation
  · Upper extremity
  · Lower extremity

Neuromuscular Syndromes

Typical Disease Patterns
Amyloidosis
CNS Involvement
Deafness
Diabetes
Endocrine
Gastrointestinal Δ
Gynecomastia
Hepatic disease
Infections
Itch
Large Nerves
Myopathy
 Occupations
Paraneoplastic
Pregnancy
Respiratory
Renal failure
Skeletal
Skin
Spontaneous motor activity
Sports
Tendon reflexes
Toxic
Tumors
   Autoantibodies
    Lab testing
  Demyelination
  Inflammatory
  Mitochondrial
  M-protein
  Nerve Biopsy
  Neuronopathy
  Vitamin & Nutrition

Go to Differential Diagnosis of Myopathies
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or newly revised
Other revisions

8/15/2012