Neuromuscular

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IMMUNOMODULATING THERAPIES FOR NEUROMUSCULAR DISORDERS

Overview
Medications
Treatment strategies

Azathioprine
Corticosteroids
  Intermittent dosing
Cyclophosphamide
Cyclosporine A
Intravenous immunoglobulin
Methotrexate
Mycophenolate mofetil
Plasma exchange
Rituxan

OVERVIEW



SPECIFIC MEDICATIONS


Corticosteroids



Prednisone
 
Glucocorticoid
Side Effects
Cushingoid features
Weight gain
Bone
  Avascular necrosis
  Osteoporosis
Myopathy
  Myosin-loss
  Type II atrophy
Diabetes
Skin: Acne; Striae
Hypertension
Psychosis & Mood change
Pseudotumor cerebri
Glaucoma
Infection


Azathioprine (Imuran)



Azathioprine

Cyclosporine A



Cyclosporine A

Methotrexate

Methotrexate

Methotrexate

Cyclophosphamide



Cyclophosphamide

Mycophenolate mofetil (CellCept)


Plasma Exchange


Human Immune Globulin


Rituximab


References: Internet sites with drug information


Return to Neuromuscular Home Page

1. J Clin Invest 2003;111:1133-1145
2. Arthritis Rheum 2006;54:607612
3. Arthritis Rheum 2006;54:621-627
4. Arthritis Rheum 2010; Online May
5. Neurology 2006;66:742744
6. Lancet Neurol 2010;90:245-253
7. Neurology 2011;77:444-452
8. Arch Neurol 2005;62:249-254
9. Cost Eff Resour Alloc 2010;8:14
10. Muscle Nerve 2015 Nov 2

12/11/2015