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Acute Immune Polyneuropathies

"Classic" Guillain-Barré
  Associated disorders
  Childhood GBS
  Clinical features
  Electrodiagnostic features
  Epidemiology
  Laboratory features
  Morbidity
  Pathology
  Prognosis
  Prodrome
  Therapy

Acute Immune Neuropathies
  Autonomic
  Motor (AMAN)
  Sensory
  Cranial nerve variants
    Ataxia & Ophthalmoplegia
    Bickerstaff
    Facial diplegia
    Miller Fisher Syndrome
    Pharyngo-Cervico-Brachial
  IgM vs GalNAc-GD1a
  Pathology

General topics
  Acute immune neuropathies
    Antibodies
    Classification
    Differential diagnosis
    General Principles
  GBS-like syndromes: Treatment

Georges Guillain



Ross & Bury 1893

Classification of Acute Immune Neuropathies

Acute immune neuropathies: General principles

Acute immune neuropathies have several features in common as well as those that vary and are distinctive for particular syndromes.
Some features suggest a different diagnosis among the causes of acute motor dysfunction.
Principles regarding which treatment to use are somewhat subjective.


"Classic" Guillain-Barré Syndrome

Autoantibodies
Clinical features
Electrodiagnostic
Laboratory
Morbidity
Other features
Pathology
Prodrome
Prognosis
Therapy

English translation: By Bassam Malo MD


Putnam 1909

Acute Motor (Axonal) Neuropathy (AMAN)

Guillain-Barré-like syndrome with serum IgM binding to GalNAc-GD1a ganglioside 2

Miller Fisher Syndrome 6

Serum IgG staining of
cerebellar molecular
layer in MFS

(Sub)Acute Sensory Neuropathies 24

Autonomic
Acute ataxic: GD1b antibodies; Acute or Relapsing
Paracarcinomatous (anti-Hu antibodies)
Sensory Guillain-Barré
Sjögren's (SSA or SSB antibodies)
Small fiber neuropathy/neuronopathy, Acute
Toxic
  Cis-platinum
  Pyridoxine intoxication

Also see: Acute neuropathies


Acute sensory polyneuropathy with some demyelinating features (Sensory Guillain-Barré)

Bickerstaff brainstem encephalitis 13


Acute neuropathies: Pharyngo-Cervical-Brachial Variant 21


Acute neuropathies: Bulbar Palsy Variant 29



Acute Immune Neuropathies: Facial Diplegia Variant (BFP) 22


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3/10/2016