Neuromuscular

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LARGE NERVES

Hereditary
  Demyelinating
    HMSN: Onion bulbs
      IA
      IB variant
        Hypertrophic radiculopathy
      III
    Refsum
  Neurofibromatosis
  Noonan syndrome + CMT1A
    Proximal nerve hypertrophy

Acquired
  Amyloidosis
  CIDP
  Multifocal motor neuropathy
  Neoplasm: Neurolymphomatosis
  Nerve Entrapment: Ulnar; Median
  Acromegaly
  Leprosy

Localized
  Hypertrophic focal mononeuropathy
    Schwann cell & perineurial
    Endoneurial fibrosis
  Peripheral nerve tumors
  Klippel-Trenaunay-Weber
  CMT IB variant
    Hypertrophic radiculopathy
Chronic Demyelinating Neuropathy

Enlarged nerves in neck (Arrow)


Nerve roots: Enlarged
Nerve roots: Enlarged

Gombault 1889


Klippel-Trenaunay-Weber syndrome
  • Clinical syndrome
    • Cutaneous capillary malformation
    • Varicose veins
    • Hypertrophy of bone & soft tissue
    • Distribution
      • Common: Single extremity, especially leg
      • Other: Multiple extremities to whole body
  • Nerves involved

Cutaneous capillary malformations



From: M Al-Lozi
Enlarged hands (L > R)


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8/8/2017