|
Congenital Myopathy Selenium deficiency |
 H&E stain |
 H&E stain |
 H&E stain |
| Myopathy: Varied muscle fiber size, Internal nuclei, Regeneration | Stippling, Basophilic | |
 Gomori trichrome stain |
 VvG stain |
 AMPDA stain |
| Stippling: Toward periphery of muscle fibers | ||
 COX stain |
 COX stain |
 COX stain |
| Mitochondria: Large; Non-uniform distribution | ||
 SDH stain |
 SDH stain |
| Mitochondria: Large; Non-uniform distribution | |
 ATPase pH 9.4 stain |
 ATPase pH 4.3 stain |
 Acid Phosphatase stain |
| Type 2 fibers are larger than type 1 Large mitochondria: More common in type 2 fibers |
Scattered type 2C muscle fibers |
Necrotic Muscle Fibers |
 Sudan stain |
 PAS stain |
| Muscle fibers: Lipid mildy increased; Glycogen increased | |