CALCIPHYLAXIS

H & E stain

Calcification of perimysial vessel walls

Alizarin red stain

Calcium deposited in vessel walls (Staining with alizarin red)

Muscle pathology in caliciphylaxis Variability in muscle fiber size Type 2 muscle fiber atrophy Muscle fiber necrosis (Not shown)

Subcutaneous tissue pathology in caliciphylaxis Alkaline phosphatase staining Hemosiderin deposits