Neuromuscular

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SPORADIC ALS

Sporadic ALS: Common forms
  Clinical features
  Diagnostic criteria
  Differential diagnosis
  Discussion of diagnosis
  Epidemiology
  Laboratory features
  Pathology
  Prognosis
  Susceptibility loci
  Treatment

Variants of ALS
  Hereditary ALS
  Primary lateral sclerosis
  Primary muscular atrophy

Multisystem disorders
  + EOM & Extrapyramidal Δ
  Fronto-Temporal dementia
  Multiple system atrophy
  Polyglucosan body disease
  Western Pacific ALS
    ALS-PD1
    ALS-PD2

From NLM

Jean Martin Charcot

MRI: FLAIR

Motor Neuron Disease (Late)
Cerebral Peduncles: Hyperintensity


Sporadic ALS: Common forms


ALS-like disorders with Fronto-Temporal Dementia (FTD) 11


Western Pacific ALS-like disorders 6


Atypical Motor Neuron Disease with Ophthalmoplegia & Extrapyramidal disorders 4


Also see Hereditary ALS


Amyotrophic Lateral Sclerosis (ALS): Discussion of the Diagnosis 1

Objectives of initial counseling Steps in the discussion

Creatine Protocols: For ALS & Neuromuscular Disorders


Motor Neuron Disease: MRI changes late in course

Hyperintense signal on MRI (FLAIR)

Medulla

Pons

Midbrain

Internal capsule

ALS: Early history of concepts


Patient information

Muscular Dystrophy Association
3300 East Sunrise Drive
Tucson, AZ 85718
Telephone 520-529-2000
FAX 520-529-5300

ALS Association (National Office)
21021 Ventura Boulevard, Suite 321
Woodland Hills, CA 91364-2206 USA
Telephone 800-782-4747

ALS Society of Canada
220 - 6 Adelaide Street East
Toronto, Ontario, M5C 1H6 CANADA
Telephone 416-362-0269
Telephone 800-267-4257 (toll-free in Canada)
FAX 416-362-0414
e-mail: alssoc@inforamp.net

Other information

Return to Motor syndromes
Go to Hereditary ALS
Return to Neuromuscular home page

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