Neuromuscular

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Presynaptic Proteins, Synaptic Vesicle Docking & Membrane Fusion 1

Active zones
Vesicle trafficking & release
  Steps
  Botulinum toxin
  Transmitter release path
Presynaptic proteins
  Ca++ & ATP regulation
  Interactions
  SNAREs
  Vesicle membrane proteins
  Secretion-related proteins
    Other


Presynaptic steps leading to transmitter release Trafficking cycle: Filling, Targeting, attachment & fusion of vesicles: Steps4 Interactions between secretion-related proteins Active Zones

SNAREs (SNAP Receptors) 5


Other secretion related proteins

Vesicle membrane proteins


Ca++ & ATP regulation


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References
1. Current Opinion in Neurobiology 1997;7:310-315 & 316-322, Annu Rev Neurosci 2004;27:509–547
2. Current Opinion in Cell Biology 1997;9:505-512
3. J. Neurochem 1997;69:1781-1792
4. Curr Opin Neurobiol 1999;9:321-328
5. Front Physiol 2017;8:5

2/12/2020