Neuromuscular

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LARGE NERVES

Hereditary
  Demyelinating
    HMSN: Onion bulbs
      IA
      IB variant
        Hypertrophic radiculopathy
      III
    Refsum
  Neurofibromatosis
  Noonan syndrome + CMT1A
    Proximal nerve hypertrophy

Acquired
  Amyloidosis
  CIDP
  Multifocal motor neuropathy
  Neoplasm
    Neurolymphomatosis
  Nerve Entrapment
    Ulnar
    Median
  Acromegaly
  Leprosy

Localized
  Hypertrophic Focal Neuropathies
    Perineurioma variant
    Endoneurial fibrosis
    Local Hypertrophic
  Peripheral nerve tumors
  Klippel-Trenaunay-Weber
  CMT IB variant
    Hypertrophic radiculopathy
Chronic Demyelinating Neuropathy

Enlarged nerves in neck (Arrow)


Nerve roots: Enlarged
Nerve roots: Enlarged

Gombault 1889


Klippel-Trenaunay-Weber syndrome
  • Clinical syndrome
    • Cutaneous capillary malformation
    • Varicose veins
    • Hypertrophy of bone & soft tissue
    • Distribution
      • Common: Single extremity, especially leg
      • Other: Multiple extremities to whole body
  • Nerves involved

Cutaneous capillary malformations



From: M Al-Lozi
Enlarged hands (L > R)


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8/8/2017