Histiocytes
Disease relations
Ultrastructure
Muscle
LHIM
Nerve
Wallerian degeneration
Perivascular
MLD
Histiocyte Ultrastructure
Nerve
Histiocyte: Free in endoneurial space
Histiocyte: With lipid droplets & myelin debris
Histiocyte: Outside Schwann cell basal lamina & Myelin sheath
Demyelinating Neuropathy
Histiocytes: Inside Schwann cell basal lamina
Demyelinating Neuropathy
A Schwann cell process neighbors the macrophage
Histiocytes
One large cell, with lipid debris, is inside a Schwann cell basal lamina
A second, smaller histiocyte (Below) is in the endoneurium
Muscle
Endomysial Histiocytes
(Arrows)
Near endomysial capillaries
See:
LHIM
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Normal nerve biopsies
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Biopsy illustrations
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Neuromuscular Home Page
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Nerve biopsy
References
1.
Neurology 2018;91:1051-1060
2.
J Neurol Neurosurg Psychiatry 2020;9:650-659
7/26/2025