Denervated Schwann Cells

Büngner bands

Collagen Pockets

Büngner Bands

Bands of Büngner:
  Large Denervated
    Schwann Cell Bands

From: R E Schmidt MD

Denervated Schwann cells: Have normal Basal lamina outside surface membrane

Small & Large Axon loss: Severe

Neurofilaments (Green); P0 (Red)
Büngner Bands stain for P0 protein: In absence of myelin (Below)
Axon loss: No staining for large or small axons (Green)

Loss of all myelinated axons

VvG stain

Loss of all axons

Neurofilament + Gomori stain

Non-Myelinating Schwann cells (NCAM stain): Remain present all through endoneurium

NCAM + Gomori

Collagen pockets

Return to Axonal loss
Go to Normal nerve
Return to Pathology & Illustrations
Return to Neuromuscular Home Page