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Transmitters | |||
---|---|---|---|
Precursors: | Preprotachykinins | ||
Synthesizing enzymes: | Peptidases | ||
Metabolizing enzymes: | |||
Metabolite: | Peptide fragments | ||
Receptors | |||
Receptor subtypes | Agonists | Antagonists | Second messenger |
NK(1) | SPOMe, GR 73632, Sar9Met(O2)11SP; Substance P |
GR82334, RP67580, CP-99994 |
PI; G-protein |
NK(2) | GR 64349; Neurokinin A |
L-659877, SR48968, MEN10207, GR94800 GR100679 |
PI; G-protein |
NK(3) | Senktide; Neurokinin B |
GR138676 | PI |