Coenzyme Q10 Deficiency: Childhood Pathology

H & E stain
Muscle fiber sizes: Varied

Gomori trichrome stain
Muscle fiber morphology: Normal

VvG stain

ATPase pH 4.3 stain
Muscle fiber types: Excessive numbers of type 2C (Intermediate stained, Above) 1

ATPase pH 9.4 stain
Muscle fiber types: Mild type 2 predominance

COX stain
Mitochondria: Mildly enlarged

SDH stain
Mitochondria: No proliferation

PAS stain
Glycogen: Increased in muscle fibers

Sudan stain
Lipid: Normal in muscle fibers

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1. Muscle Nerve 2013 Mar 14