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T-CELL Types | ||||
---|---|---|---|---|
Class | MHC Molecule | Subtypes | Function | Products |
CD4+ | Class II HLA-DP HLA-DQ HLA-DR |
Th1 | Delayed-type hypersensitivity |
IL-2
IFNγ Lymphotoxin TNFα |
Th2 | B-cell help Modulate Th1 response |
IL-4
IL-6 IL-10 |
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CD8+ | Class I HLA-A HLA-B HLA-C |
Cytotoxic cells | Lyse virus infected cells |
Perforin |
Suppressor cells | Modulate immune responses |
TGFβ
Cytokines |