Neuromuscular

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T-CELLS

T-CELL Types
Class MHC Molecule Subtypes Function Products
CD4+ Class II
HLA-DP
HLA-DQ
HLA-DR
Th1 Delayed-type
hypersensitivity
IL-2
IFNγ
Lymphotoxin
TNFα
Th2 B-cell help
Modulate Th1 response
IL-4
IL-6
IL-10
CD8+ Class I
HLA-A
HLA-B
HLA-C
Cytotoxic cells Lyse virus
infected cells
Perforin
Suppressor cells Modulate immune
responses
TGFβ
Cytokines

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5/5/98