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Utility: This protocol is for use in patients with Motor, anti-MAG & IgM M-protein-related neuropathies.

Treatment regimen: During each cycle of treatment patients receive During a course of therapy this regimen is given Precautions taken to avoid side effects include:
  1. Fluid: Administration of 3-4 liters of fluid on the days of Cytoxan treatment.
  2. Antiemetics - Zofran (Ondansetron) 0.15 mg/kg over 15 minutes: Give
  3. Strict I&O should be kept during the patient's hospital stay.
  4. Urine: During and 1 day after treatment
  5. After administration of Cytoxan, IV tubing should be changed before resuming regular IV hydration.
  6. Blood tests: Obtained before the first treatment and at intervals thereafter.
  7. Follow-up - Return outpatient appointment is 1 to 2 months after the last treatment.
  8. Nursing precautions should include:
Outcome assessments
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