Neuromuscular

MUSCLE FIBER STRUCTURE & FUNCTION

Muscle fiber
  Contraction
  Crossbridges
  Excitation-Contraction-Relaxation cycle
  Structure



EXCITATION-CONTRACTION-RELAXATION CYCLE

  1. Motor neuron activity triggers sarcolemmal depolarization via NMJ
  2. Action potential generated
  3. Ca++ ions released from sarcoplasmic reticulum: Regulated by 2 large membrane protein complexes
  4. Contractile apparatus activated

MUSCLE FIBER STRUCTURE

Muscle fiber structure
From UCSD


THICK-THIN FILAMENT CROSSBRIDGES

Crossbridge
From M Ferenczi


MUSCLE FIBER CONTRACTION

Sarcomere contraction
From M Ferenczi



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6/14/2002