FASCIITIS (Perimyositis)
H&E stain
H&E stain
H&E stain
Muscle morphology
Lesions are largely confined to perimysium & epimysium (not shown).
Perimysium is fragmented & necrotic.
Some regions are dark & hyaline.
Others are rarified & lucent.
Neighboring muscle fibers are relatively unaffected.
Cells in regions of perimysial damage have large nuclei & pink cytoplasm
Esterase stain
Esterase stain
H&E stain
Inflammation
Most cells in regions of perimysial damage are macrophages.
The cells stain for esterase & acid phosphatase.
Occasional regions of undamaged perimysium contain mononuclear cell infiltrates (Right).
Fasciitis: MRI
Multiple regions of increased T2 signal in leg muscles (L > R)
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Inflammatory myopathies
5/13/2002
