![]() H & E stain |
Morphology Muscle fibers Small & Intermediate-sized Angular & Polygonal Hypertrophic Internal nuclei: Often multiple Grouped muscle fiber atrophy |
![]() H & E stain |
Internal nuclei![]() Congo red stain |
Pyknotic nuclear clumps![]() Congo red stain |
Internal architecture: Irregular in larger muscle fibers![]() NADH stain |
![]() NADH stain |
![]() VvG stain Chronic changes Internal nuclei Partial fusion of muscle fibers Capillary inside muscle fiber Pyknotic nuclear clumps |
![]() Gomori trichrome stain |
Cytoplasmic bodies in a small muscle fiber![]() Gomori trichrome stain |
Muscle fiber types: Type 1 predominance; No fiber type grouping![]() ATPase, pH 9.4 |
Vacuoles in Muscle fibers![]() H & E stain |
![]() H & E stain |
![]() Gomori trichrome stain |
![]() Congo red stain Vacuoles Contain basophilic granular debris May be near eosinophilic cytoplasmic bodies |
![]() Congo red stain |
![]() Congo red stain |
![]() Congo red stain |
Aggregates Irregular; Dark; Cytoplasmic May be near or around internal nuclei ![]() Caveolin-3 stain |
![]() Caveolin-3 stain |
Caveolin-3 may also stain rim of vacuoles![]() Caveolin-3 stain |
Caveolin-3 staining around internalized capillary![]() Caveolin-3 stain |