NEUROMUSCULAR JUNCTIONS
Neuromuscular Junction
Presynaptic Axon Terminal: Brown Arrow
Vesicles: Clustered near post-synaptic folds
Mitochondria: Present in axon terminal cytoplasm
Terminal Schwann Cell (Telodendroglia): Black Arrow
Surrounded by pale Basal lamina
Post-synaptic Folds: Green Arrow
AChRs: Concentrated at top of folds, near nerve terminal
Na+ Channels: Concentrated at bottom of folds
Note Basal lamina layer within folds
Acetylcholinesterse: Located in Basal lamina
NMJ Myonucleus: Red Arrow
Molecular program has specificity for NMJ molecules
Endomysial Fibroblasts (Left): Long, thin cell processes
Muscle Fiber (Bottom Right): Sarcomeres cut in cross-section; Lipid droplets (2)
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Neuromuscular Junction: Ions & Molecules
From: Tulane
8/2/2024