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Transmitters | |||
---|---|---|---|
Precursors: | None | ||
Synthesizing enzymes: | None | ||
Inactivation: | Reuptake Glutamate transaminase | ||
Metabolite: | Glutamine | ||
Receptors | |||
Receptor types | Agonists | Antagonists | Second messenger |
NMDA | NMDA, CPP, trans-2,3-PDA, (-)-cis-1-ACPD |
CGP37849 MK801: Channel blocker; PCP: Non-competitive AP5 & AP7 |
Ca++ Mg++: Voltage sensitive Glycine: Regulatory |
AMPA:
1
; 2 ; 3 ; 4 |
AMPA, Quisqualate |
NBQX, CNQX DNQX |
Cation conductance |
Kainate | Kainate, Domoate |
NBQX, CNQX DNQX |
Cation conductance |
Metabotropic | 1S,3R-ACPD, Ibotenate |
None | PI; G-protein |