Neuromuscular

PATHWAYS: GLYCOGEN & GLUCOSE

Glucose to pyruvate: Animation
Glycogenolysis
Glycolysis
Glycogen disorders


GLYCOGENOLYSIS PATHWAY

Glycogenolysis
  • Glycogen phosphorylase
    • Removes glucose residues from α-(1,4)-linkages within glycogen molecules
    • Product of reaction: Glucose-1-phosphate.
  • Phosphoglucomutase
    • Converts glucose-1-phosphate to glucose-6-phosphate.
    • Skeletal muscle: Glucose-6-phosphate is then metabolized by the glycolytic pathway.
  • Phosphorylase b kinase
    • Reactivates phosphorylase by phosphorylating it
  • Debrancher enzyme
    • Removes glucose from branch points (α-(1,6)-linkages) within glycogen
  • Hexokinase

GLYCOLYSIS PATHWAY



From MW King
Progressive changes
Glycolysis of glucose to pyruvate.

A = Adenosine
P = Phosphate

From University of Virginia




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3/10/2004