PATHWAYS: GLYCOGEN & GLUCOSE

GLYCOGENOLYSIS PATHWAY

Glycogen phosphorylase Removes glucose residues from α-(1,4)-linkages within glycogen molecules Product of reaction: Glucose-1-phosphate. Phosphoglucomutase Converts glucose-1-phosphate to glucose-6-phosphate. Skeletal muscle: Glucose-6-phosphate is then metabolized by the glycolytic pathway. Phosphorylase b kinase Reactivates phosphorylase by phosphorylating it Debrancher enzyme Removes glucose from branch points (α-(1,6)-linkages) within glycogen Hexokinase Phosphorylates this glucose Phosphorylated glucose then enters the glycolytic pathway

GLYCOLYSIS PATHWAY

From MW King

Progressive changes Glycolysis of glucose to pyruvate. = Adenosine = Phosphate From University of Virginia