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SCLEROMYXEDEMA

Patterns of pathology in muscle

H & E stain	H & E stain
Atrophic muscle fibers Especially common in perifascicular regions May be near perimysial cellularity (Arrow) Often basophilic Shape: Rounded or Polygonal May contain vacuoles
H & E stain	H & E stain
Vacuoles: Rimmed
H & E stain	PAS stain
Cells in perimysium: Large; PAS positive

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7/18/2019