Trunk Muscles
![](../pics/biopsy/control/scalene/scalenehe.jpg)
H&E stain
|
Fiber size: Mild variation
Endomysial connective tissue: Normal
Perimysial Vessels: Normal
![](../pics/biopsy/control/scalene/scalenehe2.jpg)
H&E stain
|
![](../pics/biopsy/control/scalene/scalenecr.jpg)
Congo red stain
|
Nuclei: Normally present at periphery of muscle fibers
![](../pics/biopsy/control/scalene/scalenegt2.jpg)
Gomori trichrome stain
|
Internal architecture: Mildy prominent or coarse
![](../pics/biopsy/control/scalene/scalenevvg.jpg)
VvG stain
|
Internal architecture
![](../pics/biopsy/control/scalene/scalenenadh2types.jpg)
NADH stain
|
Internal architecture
Varied degrees of coarseness & irregularity
"Alveolar" fibers: Similar to those seen in CACNA1S congenital myopathy
![](../pics/biopsy/control/scalene/scalenenadh1type.jpg)
NADH stain
|
Some muscle fibers have
Internal clear regions
Irregular internal architecture
![](../pics/biopsy/control/scalene/scalenenadh3.jpg)
NADH stain
|
![](../pics/biopsy/control/scalene/scaleneatplp.jpg)
ATPase pH 9.4 stain
|
Fiber types
Some fascicles, or entire muscles, can have marked type I fiber predominance
Fiber type proportions can vary among fascicles
![](../pics/biopsy/control/scalene/scalene1atp94mp.jpg)
ATPase pH 9.4 stain
|
No fiber type grouping
![](../pics/biopsy/control/scalene/scaleneatp94hp.jpg)
ATPase pH 9.4 stain
|
![](../pics/biopsy/control/scalene/scalenealpmp.jpg)
Alkaline phosphatase stain
|
Endomysial capillaries
Some, more than in limb muscles, stain for alkaline phosphatase
![](../pics/biopsy/control/scalene/scalenealphp.jpg)
Alkaline phosphatase stain
|
Muscle: Other Structures
Muscle structures
Vessels
Arteries: Fibrillar internal layer
Veins: (Black arrows): Wall may have no fibrils (Above) or many curved fibrils (Below)
Endomysial capillaries (White arrow)
Spindle (Contains small round muscle fibers)
Intramuscular nerve (Myelinated axons are dark-stained)
Perimysium: Connective tissue between fasciclas (Pink-stained): Contains irregular fibrils
Vascular perimysium: Contains intermediate-sized arteries & veins + lymphatics
Avascular perimysium: Contains no vessels
Avascular Perimysium
Return to
Pathology index
Return to
Neuromuscular Home Page
5/10/2020