Neuromuscular

Immune Myopathy with Large (Megaconial) Mitochondria


H&E stain
From: T Liewluck
Myopathy
  Muscle fiber sizes: Varied
  Mitochondria: Stained as cytoplasmic dots in muscle fibers

Gomori trichrome stain
From: T Liewluck

Mitochondrial Pathololgy
  Many large mitochondria in muscle fibers: Often present in clusters, or at periphery of muscle fibers

Cytochrome oxidase stain
From: T Liewluck


From: O Ni
Mitochondria: Varied sizes, one very large

Mitochondrion: Large with complex cristae
Glycogen granules: Surround mitochondria in cytoplasm
Sarcolemma: Irregular with breaks

From: O Ni

Return to Inflammatory myopathies
Return to Immune Megaconial Myopathy

11/23/2024