LGMD 2C: γ-Sarcoglycan Deficiency
 H & E stain Muscle fiber necrosis & regeneration Increased endomysial connective tissue Varied muscle fiber size |
 H & E stain |
 GT stain |
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Increased endomysial connective tissue Varied muscle fiber size | |
 ATPase pH 4.3 stain |
 Alkaline phosphatase stain |
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Many immature muscle fibers Intermediate staining on ATPase pH 4.3 Positive staining on alkaline phosphatase | |
Acid phosphatase stain Necrotic muscle fibers Pale staining Contain Acid phosphatase positive phagocytic cells (macrophages) |
 γ-Sarcoglycan stain Reduced γ-sarcoglycan staining |
 γ-Sarcoglycan stain Control muscle: Normal γ-sarcoglycan staining |
Return to Neuromuscular
Return to LGMD 2C, γ-Sarcoglycan Deficiency
10/31/2003