MYOPATHY WITH IgM ANTI-DECORIN (BJ) ANTIBODIES

Muscle Fiber Pathology H&E stain Muscle fiber size is variable. Small muscle fibers Are rounded or polygonal May have abnormal internal architecture Endomysial connective tissue is increased. Multiple, large internal nuclei may be present within muscle fibers (Right)

Muscle Fiber Internal Architcture NADH stain Irregular, moth-eaten, internal architecture.

Immuno-Pathology IgM (brown) stains vessels, and muscle basal lamina, endomysium and perimysium, but not muscle fibers.

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Return to Anti-Decorin (BJ) Myopathy

1/13/2001