Neuromuscular

MACROPHAGIC MYOFASCIITIS


H&E stain

H&E stain
  • Cellular infiltrates
    • Large in endomysium & perimysium.
    • Cells: Large; Abundant cytoplasm; Esterase & PAS positive.
    • No granulomas
  • Muscle fibers
    • Not prominently affected.
    • No degeneration or regeneration.
  • Fascia (perimysium): No necrosis


Esterase stain

Esterase stain
Cells in infiltrates are mostly macrophages
& stain strongly with esterase.

PAS stain
Infiltrating cells stain positively with PAS



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5/3/98