Neuromuscular

Muscle: Fetal

Extramedullary hematopoesis
Fascicles
Muscle fibers
Nerves: Intramuscular
Organizarion
Spindles
Vessels

Organization


H & E stain
Vessels
  Arteries & Veins: In bundles
  Arterioles: In center of fascicles (in Vascular perimysium)
Muscle fibers
  In fascicles
  Surrounded by avascular perimysium

Gomori trichrome stain

VvG stain

Fascicles of Muscle fibers


VvG stain
Fascicles
  Surrounded by avascular perimysium
  Contain Arterioles & Veinules in center (Arrow)

VvG stain

Muscle fibers


H&E stain
Muscle fibers
  Sizes: Small (3 to 10 µM diameter)
  Nuclei: Large; Irregular shapes

H&E stain

Gomori trichrome stain

Fiber types: Checkerboard pattern of types 1 & 2

ATPase pH 4.3 stain

Vessels


Gomori trichrome stain
Vessels
  Arteries
    Inner layer: Contains continuous elastin layer; Different from fibrillar structure in older people
    Smooth muscle layer: Moderately thick
    Surround: Connective tissue; More prominent than in older patients

VvG stain

Artery

VvG stain

Vein
  Thinner wall
  Contains irregular fibrils

VvG stain


Alkaline phosphatase stain
Feeder capillaries: In endomysium

Alkaline phosphatase stain

Spindles


H & E stain

Gomori trichrome stain

VvG stain


Acid phosphatase stain
Acid phosphatase positive cells: Few; scattered in endomysium & Perimysium

Acid phosphatase stain

Fetal muscle: Extramedullary Hematopoesis


Gomori trichrome stain
Extramedullary Hematopoesis
  Cells surrounding smaller vessels in vascular perimysium
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H&E stain

H&E stain

Intramuscular Nerves
  Axons surrounded by myelin

VvG stain

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6/11/2017