Cystinosis
 H&E stain |
 H&E stain |
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Muscle fibers: Varied sizes
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Muscle fibers: Vacuoles, irregular shaped; Large nuclei
|
 VvG stain |
Vacuoles in muscle fibers VvG stain |
 Gomori trichrome stain; From C Cai |
 NADH stain Internal architecture Irregular Linearization in pale stained fibers |
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Vacuoles: Contain Basophilic granular debris Red-green birefringent material  Congo red stain |
 Congo red stain |
  Congo red stain |
AMPDA positive agggregates: Some associated with vacuoles
 AMPDA stain |
 AMPDA stain;/ From C Cai |
Acid phosphatase positive material: Some associated with, or within, vacuoles
 Acid phosphatase stain |
 Acid phosphatase stain; From C Cai |
Immature muscle fibers ATPase pH 4.3 stain |
 From C Cai |
 From C Cai |
 From C Cai |
 From C Cai |
Return to Cystinosis
Return to Muscle biopsies
10/8/2019