Neuromuscular

IV Lymphoma (Angiotropic B-cell)

Lymphoma cells in vessels

H&E stain

H&E stain

H&E stain
Large neoplastic B-cells in small & intermediate sized vessels


H&E stain


NADH stain
Hemosiderin (Brown) in connective tissue

Acid phosphatase stain
Positive staining cells in vessel walls

Intravascular cells in endoneurium stain for
  Leukocyte common antigen


Vessel walls stain for Ulex lectin


CD20 stain   From: A Perry
CD20+ cells in vessels & connective tissue

CD20 stain
CD20+ cells in vessel lumen

CD20 stain
CD20+ cells in vessel walls


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9/8/2010