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Marinesco-Sjögren Syndrome

From: I Nishino

H&E stain Muscle fiber size: Varied Endomysial connective tissue: Mildly increased Vacuole (1 fiber): Contains basophilic material

H&E stain Muscle fiber size: Varied   Scattered very small fibers   Some small fibers are basophilic Internal nuclei

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H&E stain Muscle fiber with large vacuole   Vacuole contains basophilic material

Gomori trichrome stain Muscle fiber with vacuole   Vacuole contains red material

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Gomori trichrome stain Muscle fiber with 2 vacuoles   Vacuoles contain red material   Nucleus is adjacent to 1 vacuole

Non-specific esterase stain Nuclear staining within several fibers

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NADH stain

ATPase pH 10.5 stain

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6/3/2008