Neuromuscular

Unknowns: Neuropathic-like disorders

Each of these biopsies is from a patient with a neuropathy.
What is the most likely diagnosis?

A

H & E stain
What are causes of small angular muscle fibers?
What stains are useful in this differential diagnosis?


B

ATPase pH 9.4 stain
What disease most commonly produces this pattern of muscle fiber types & size changes?


C

NADH-TR stain
What processes produce this anatomical change in muscle fibers?
What muscle most frequently shows this change?
Could these be cores?


D

ATPase pH 9.4 stain
What disease most commonly produces this pattern of muscle fiber types & size changes?


E

VvG stain
What is this structure (arrow)?
What stains best visualize it?


F

H & E stain
What is this dark stained structure (arrow)?
How did it develop?
What disorders can produce it?




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12/30/2010