Ring fibers & Sarcomere disorientation

NADH stain

H&E stain

Congo red stain
Ring fibers
  • NADH & AMPDA stains: Ring of striations, perpendicular to normal orientation, around circumference of muscle fiber
  • H & E stain: Internal, ring-shaped, dark-staining regions in small fibers
  • Congo red: "Amorphous" ring in a muscle fiber with paler central region

NADH stain

AMPDA stain

NADH stain
  • Dark staining sarcoplasmic pad around rim of fiber (Right)

Return to Neuromuscular Home Page
Return to Myopathy with Ring fibers