Neuromuscular

Reducing Body Myopathy

From: CG Bonnemann MD


H & E stain
Reducing bodies: Irregularly shaped, cytoplasmic inclusions
Muscle fiber size: Varied


Gomori trichrome stain
Reducing bodies:
  Darkly stained on Gomori trichrome


Menadione-NBT stain
Reducing bodies: Stain positively with Menadione-NBT

Reducing bodies: Ultrastructure
  Structure: Granular tubulo-filamentous material (17 nm in diameter)
  Location: At periphery of sarcoplasm & around nucleus

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11/18/2015