Hereditary Inclusion Body Myopathy: Type 2

Muscle: General features

H&E stain Muscle fiber size: Varied Smaller fibers may be clustered Endomysial connective tissue: Not prominently increased

H&E stain Small, angulated muscle fibers with vacuoles

NADH stain Scattered muscle fibers with coarse internal architecture

ATPase pH 9.4 stain Type 1 muscle fiber predominance

Vacuolated muscle fibers

H&E stain

Gomori trichrome stain

NADH stain

H&E stain

Congo red stain

Congo red stain

Congo red stain

Congo red stain