 H&E stain Progressive phagocytosis of muscle fibers by large multinucleated cells. Muscle fibers have a hyaline appearance. They are necrotic and probably not viable. |
 Congo red stain Progressive phagocytosis of muscle fibers by large multinucleated cells. |
 NADH stain Multinucleated phagocytic cells are strongly NADH positive. Necrotic muscle fibers are pale and have lost NADH staining. |
 Alkaline phosphatase stain |
 Acid phosphatase stain |
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Alkaline phosphatase (Left): Hemophagocytic cells stain strongly. Acid phosphatase (Right): Hemophagocytic cells stain weakly. Neighboring activated macrophages stain red. |
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