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 H&E stain |
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Variable fiber size: Atrophy & Hypertrophy Regenerating muscle fibers (Basophilic) Endomysial connective tissue: Moderately increased Inflammation: Around intermediate sized vessel | |
 ATPase, pH 4.3 stain Small & large fibers are both types.
A few immature, type 2C, fibers are present. (Intermediate staining; Arrow) |
 Sudan black stain Lipid droplets are accumulating in the perimysium. |
 H&E stain Biopsy from another FSH patient
More marked variation in fiber size |
 NADH stain Hypertrophied fibers have pale centers.
Some small fibers are darkly stained |
 ATPase pH 9.4 stain, Patient 1 Large fibers are type I & II.
Small fibers are type I & II. |
 ATPase pH 9.4 stain, Patient 2 Large fibers are type I & II.
Small fibers are often type II. |
 H&E stain |
 ATPase pH 9.4 stain |
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Variable muscle fiber size. Basophilic (immature) fibers. No hypertrophy. Endomysial inflammation. |
Small fibers are Type I & II
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