Neuromuscular

Denervated Schwann Cells


Büngner bands

Collagen Pockets



From: R E Schmidt MD

Bands of Büngner:
  Large Denervated
    Schwann Cell Bands


Denervated Schwann cells: Have normal Basal lamina outside surface membrane


Small & Large Axon loss: Severe


Neurofilaments (Green); P0 (Red)
Büngner Bands stain for P0 protein: In absence of myelin (Below)
Axon loss: No staining for large or small axons (Green)

Loss of all myelinated axons

VvG stain

Loss of all axons

Neurofilament + Gomori stain

Non-Myelinating Schwann cells (NCAM stain): Remain present all through endoneurium

NCAM + Gomori

Collagen pockets





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3/21/2017