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AZT Myopathy

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Scattered muscle fibers with irregular structure

H&E stain

H&E stain

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Muscle fibers with Lipid storage (Round clear regions) or Mitochondrial proliferation (Red)

Gomori trichrome stain

Gomori trichrome stain

Cytochrome oxidase (COX) stain

Many, scattered COX-negative muscle fibers Cytochrome oxidase (COX) stain

Scattered SDH-positive muscle fibers Succinate Dehydrogenase (SDH) stain

Succinate Dehydrogenase (SDH) stain

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Lipid storage (Large black droplets) in some muscle fibers Sudan Black stain

NADH stain

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1/13/2021