Neuromuscular

AZT Myopathy


Scattered muscle fibers with irregular structure

H&E stain

H&E stain

Muscle fibers with Lipid storage (Round clear regions) or Mitochondrial proliferation (Red)

Gomori trichrome stain


Gomori trichrome stain


Cytochrome oxidase (COX) stain
Many, scattered COX-negative muscle fibers

Cytochrome oxidase (COX) stain

Scattered SDH-positive muscle fibers

Succinate Dehydrogenase (SDH) stain

Succinate Dehydrogenase (SDH) stain

Lipid storage (Large black droplets) in some muscle fibers

Sudan Black stain


NADH stain

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12/16/2015