Home, Search, Index, Links, Pathology, Molecules, Syndromes,
Muscle, NMJ, Nerve, Spinal, Ataxia, Antibody & Biopsy, Patient Info
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Home, Search, Index, Links, Pathology, Molecules, Syndromes, Muscle, NMJ, Nerve, Spinal, Ataxia, Antibody & Biopsy, Patient Info |
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| Early Pathology: Necrosis & Regeneration |
Early Pathology: Myopathic Groups |
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| Angular Fibers: NADH staining | Later pathology: Increased connective tissue |
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| Perimysial inflammation Hypertrophic muscle fibers |
Perivascular inflammation |
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| Normal: Dysferlin around muscle fibers |
LGMD 2B: Absent dysferlin |
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| Sarcolemma: Focal lesion | Sarcolemma: Focal projections |
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| Subsarcolemmal region: Vacuoles | Subsarcolemmal region: Disrupted internal architecture |
Leg MRI: Involvement of posterior-medial gastrocnemius
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Thigh MRI: Involvement of posterior muscles
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